Architecturally, Stambaugh Auditorium is a free rendition of the classic as a exemplified in the Italian Renaissance. The structure was modeled after the public auditorium in Springfield, Massachusetts, which in turn was designed from the Pantheon in Paris. Helmle and Corbett Architects of New York City were the creators.

Originally intended to be erected either downtown or at the center of Wick Park, the 300 by 70 site at 1000 Fifth Avenue proved to be a wise choice, one which was enlarged to provide for parking areas when more land became available. Indiana limestone was used for the exterior walls. Inside areas feature top quality oak paneling, marble benches and again Indiana limestone.